Recent Posts

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New Theories / Estrogen-mediated coagulopathy
« Last post by smart on May 09, 2021, 04:58:56 PM »
Abstract

New evidences suggest estrogen-mediated coagulopathy is a atypical form of VITT (Vaccine-induced immune thrombotic thrombocytopenia) associated to the activation of platelet factor 4 (PF4) by thromboplastin complexes (CD142) in megakaryocytes (MK) cells [1-3].

Likewise, oral contraceptives and estrogen by itself can induce pro-thrombotic phenotype in womens following endothelial exocytosis. [4]


This mechanism is currently not well-understood and further research should investigate the role of CD142 complexes in thrombosis.

Consequently, these results may suggests a novel role for estrogen signaling in the etiology of vaccine-mediated thrombocytopenia.

-smart


References:

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627332/
2. https://ashpublications.org/blood/article/135/15/1270/452528/Recognition-of-PF4-VWF-complexes-by-heparin
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345022/
4. https://www.sciencedirect.com/science/article/abs/pii/S0006291X2100615X


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Just Chat / -
« Last post by RonaldVok on May 09, 2021, 11:10:59 AM »
Thats all we need also. Can anybody tell uss about the hotels, Anthony, do you have any good deals in March?

JWA
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Just Chat / Re: Hello all
« Last post by smart on April 30, 2021, 05:29:33 AM »
Welcome aboard John from Carrollton, Texas.  I look forward to seeing some of your posts and also getting to know you.  All the best.

Welcome aboard John. Let me know if you have any issues with the forum that you would like to fix.

smart
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Just Chat / -
« Last post by RonaldVok on April 30, 2021, 03:44:54 AM »
Welcome aboard John from Carrollton, Texas.  I look forward to seeing some of your posts and also getting to know you.  All the best.
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Just Chat / Tell us about yourself....
« Last post by smart on April 27, 2021, 05:10:46 PM »
Hi world i am Jack Bortone (aka smart) and welcome to Applied Human Neurosecurity Forum. I wish you'll find this forum useful for you, either by raising awareness in human neurosecurity or by having a good time here. I am a independent and freelance scientist based in Ste-Sophie (Quebec). I am currently single and got no kids. Maybe one day i'll want to have kids, but reaching 40, i have other urgent priorities in my life.

Hence, i developed this forum in order to raise awareness about human neurosecurity. Sometimes i'm wondering if writing a book could have been a wiser option to explain my dream and concept of open neurosecurity access to all...  ???

So far, i'm being busy mostly on Twitter and kinda ignored posting any relevant threads here. Im terribly sorry for this mistake. I do constant errors in whatever i project doing and sometimes things go wrong. I believe i have developed a positive way of learning when doing errors and i always try hard to understand myself in the process.

Human neurosecurity is the future of public mental health. It is a dream i've started wandering about a few years ago, once i started to live without physical friends on a semi-permanent basis. I have the innate capacity in me to withstand and cope with great periods of loneliness, both emotionally and physically.

Besides, i love working with computers as always... My initial dream was to become a programmer. I went on studying python but it went nowhere, so i moved into science, a domain that consistently keeps me in the student chair, as i like to exercise my own dialectical thinking skills when studying the human brain.

Anyway, thats all for now. I will be happy to read more about you once real users will join this forum.  ;D

Best wishes,
smart
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Human neurosecurity and intelligence / Re: What is safety conditioning
« Last post by smart on April 23, 2021, 05:27:14 PM »
Stress dependent dopaminergic activity caused by prolonged mask use can affect control of fear-extinction and reward processing within the ventral striatum by altering phasic dopamine signaling: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032992/
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Neuroimmunity / MOVED: Restless legs syndrome
« Last post by smart on April 21, 2021, 01:11:31 AM »
This topic has been moved to Medicine.

https://open-neurosecurity.org/forum/index.php?topic=134.0
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Human neurosecurity and intelligence / Re: What is safety conditioning
« Last post by smart on April 21, 2021, 12:57:32 AM »
"The PVN sends dense projections to the nucleus tractus solitarii (nTS), a region that displays neuronal activation following hypoxia."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425639/
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General Discussion / MOVED: Free human neurosecurity training for all
« Last post by smart on April 18, 2021, 08:24:02 AM »
This topic has been moved to Human neurosecurity training.

https://open-neurosecurity.org/forum/index.php?topic=97.0
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Human neurosecurity training / Re: Free human neurosecurity training for all
« Last post by smart on April 18, 2021, 08:21:10 AM »
By promoting the continuous education of people towards self-controlling behavior and related neuronal activity, free dialectical neurosecurity training can enhance dynamic learning of conscious experiences. Hence, by exercising dialectical neurosecurity oneself can also increase experimental outcomes associated to a specific conscious activity or internal cue.   
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