Applied Human Neurosecurity Forum

Applied human neurosecurity => Human neurosecurity and intelligence => Topic started by: smart on April 11, 2021, 06:41:34 PM

Title: Re: What is safety conditioning
Post by: smart on April 11, 2021, 06:41:34 PM
Original thread is here: https://www.thenakedscientists.com/forum/index.php?topic=82121.0
Title: Re: What is safety conditioning
Post by: smart on April 11, 2021, 06:52:54 PM
This is a test!  ;)
Title: Re: What is safety conditioning
Post by: smart on April 16, 2021, 12:29:58 AM
Useful links on safety conditioning:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878001/
https://www.jneurosci.org/content/35/8/3470
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130622/
Title: Re: What is safety conditioning
Post by: smart on April 16, 2021, 12:59:03 AM
Key points:

1. "NAccSh c-Fos is activated in animals performing SigAA"

2. My experimental findings suggests chronic/intermittent mask wearing may mimic the psychomotor effects of cocaine addiction by modulating stress-dependent dopamine (D2) receptors in the ventral striatum and nucleus accumbens shell (NAccSh): https://www.pnas.org/content/113/41/11609
Title: Re: What is safety conditioning
Post by: smart on April 17, 2021, 10:13:04 AM
3. Persistent surgical mask use alters dopamine neurotransmission dynamics in the ventral striatum and amygdala via stress-dependent modulation of the noradrenergic system, thereby promoting conditioned avoidance learning in healthy adults. In particular this problematic behavior may induces cortisol-mediated anxiogenic effects by modulating stress-dependent dopamine D2 connectivity in the ventral striatum, thereby facilitating striatal-based memory retrieval while downregulating amygdala-hippocampal activity: https://onlinelibrary.wiley.com/doi/10.1111/ejn.14942
Title: Re: What is safety conditioning
Post by: smart on April 21, 2021, 12:57:32 AM
"The PVN sends dense projections to the nucleus tractus solitarii (nTS), a region that displays neuronal activation following hypoxia."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425639/
Title: Re: What is safety conditioning
Post by: smart on April 23, 2021, 05:27:14 PM
Stress dependent dopaminergic activity caused by prolonged mask use can affect control of fear-extinction and reward processing within the ventral striatum by altering phasic dopamine signaling: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032992/